Adrafinil Info – Dosage, Side Effects & Reviews

Javier

Last Updated June 21, 2022

Adrafinil Information

Adrafinil is a relatively new alertness promoting nootropic or “smart drugs”. It has come to light recently as a legal replacement to Modafinil. Both being powerful eurgeroic agents means they can act on the bodies ability to stay awake and be in a state of locked in focus for many hours at a time. Although not commonly understood, Adrafinil is actually known as a pro-drug, in that it is able to convert directly into Modafinil in the bodies metabolic systems. There are many other successful drugs which act in this way such as Codeine>Morphine. Generally the effects of Adrafinil are comparably similar to those of Modafinil, however there are some slight difference in subtle feeling and duration. Adrafinil, is a popular nootropic as it is very easy to buy online using accredited nootropic stores, and what’s more is you can order safely using normal card processors and Paypal-unlike with Modafinil.

Adrafinil is actually known as a pro-drug

Many drugs have their generic name, however their trade name is assigned by the company which first patented and synthesised the chemical. French pharmaceutical company Lafon first synthesised Adrafinil (known in tests as CRL-40028) and gave it the trade name Olmifon. It was first indicated as a treatment for those suffering from excessive daytime fatigue for those with illnesses and for those with shift work that required unusual working times. It is also marketed to aid in focus and attention for those who suffer from ADHD (attention deficit hyperactivity disorder). So how exactly does this chemical act within the body to create this effect? Well, some studies have suggested a mechanism involving a hormone known as hypercretin, which is able to facilitate the feeling of wakefulness. The more hypercretin your body has access to to, the higher your levels of certain neurotransmitters such as dopamine, and histamine. It is also able to increase levels of adrenalin, which when combined with the other two neurotransmitters mentioned, can induce a powerful state of attention. Consequently, many students, athletes and professional have chosen Adrafinil as the proffered supplement for their study sessions, workouts or day-to-day activities.

Simply having the energy to do something does not mean you will enjoy it!

As touched on earlier, adrafinil is able to manipulate levels of rewards hormones such as dopamine and serotonin although to a much lesser extent. This means that users have reported a small but significant mood boost when taking Adrafinil. This is strangely important, because those who are working on a somewhat tedious task, are able to work long hours with a general good mood and this is important in maintain moral and working through the task. Simply having the energy to do something does not mean you will enjoy it. It is also thought that Adrafinil can act on the bodies glutamate receptors and promote wakefulness through this mechanism. Other popular nootropics such as Aniracetam ans Piracetam have also been implicated in this cognitive pathway and so it is not unlikey that Adrafinil may have a similar action and end result. Glutamate is extremely important in learning, memory and synaptic plasticity.

Unlike other nootropics which are generally regarded to have very subtle actions of memory and stimulation, adrafinil generally receives very positive reviews from even the most sceptical users. This is because the peripheral feeling of stimulation is very apparent, and although you may not instantly feel a “rush” you will definitely know that you were “on something” the following day. Most people will describe Adrafinil as the best nootropics they have tried, other than Modafinil.
Generally, after reading the subjective user reports of the difference between Adrafinil and Modafinil the consensus seems to point towards a slightly longer peak plasma time (time it takes for the drug to be at full concentrations in your body) and a slightly lower efficacy with regards to dosage. Although these difference are present, they are subtle, and the nootropic community has accepted Adrafinil as a more than adequate substitute for Modafinil. Do not push it too far…..you should not over do it Although individual reactions will vary with any substance, it is suitable to take anywhere from 150mg to 300mg a day, depending on your desired effect. The best option is to try a small amount and gauge your dose after the first effects, some people will need more and some less. Being water soluble, many decide to simply mix the pure powder in with water and sip slowly, whereas, others will prefer a capsule. It should be noted that capsules will incure more costs if ordered in this form, so it maybe best (time permitting) to encapsulate yourself. Do not push it too far, although being a nootropic by definition, you should not over do it, and you should always practice due diligence beforehand.[/tab] [/tabcontent] [/tabs]


Modafinil Vs Adrafinil

Generally, after reading the subjective user reports of the difference between Adrafinil and Modafinil the consensus seems to point towards a slightly longer peak plasma time (time it takes for the drug to be at full concentrations in your body) and a slightly lower efficacy with regards to dosage. Although these difference are present, they are subtle, and the nootropic community has accepted Adrafinil as a more than adequate substitute for Modafinil.

Do not push it too far…..you should not over do it

Although individual reactions will vary with any substance, it is suitable to take anywhere from 150mg to 300mg a day, depending on your desired effect. The best option is to try a small amount and gauge your dose after the first effects, some people will need more and some less. Being water soluble, many decide to simply mix the pure powder in with water and sip slowly, whereas, others will prefer a capsule. It should be noted that capsules will incure more costs if ordered in this form, so it maybe best (time permitting) to encapsulate yourself. Do not push it too far, although being a nootropic by definition, you should not over do it, and you should always practice due diligence beforehand.


Are there side effects with Adrafinil?

Generally, when compared to normal stimulants, there is little incidence of adverse drug reactions with adrafinil. However, that said, you should be aware that Adrafinil may cause an elevated heartbeat and elevated blood pressure. This type of reaction is the sort of thing you may experience if you had a strong coffee so don’t be alarmed. One important point is that adrafinil does not exhibit the strong side effects you would see in drugs such as amphetamines or other common stimulants.

The main concern in the nootropics community is that of possible adrafinil liver toxicity which has been discussed in some forums. This may occur because Adrafinil is a pro-drug, it requires the liver to be actively converting it into the active metabolite-Modafinil, this will undoubtedly put some extra strain on the liver. The extent of this strain is fully dose dependant. Some have pointed out that the relative risk it possess is akin to that posed by taking Tylenol (an opiate painkiller). However, In healthy individuals with normal liver function it is not necessary to worry about this side effect. Simply take it slow, know your body and reactions and keep everything in moderation. Of course, if anything bad does happen and you do not feel right, seek professional medical advice at once.


So where can I buy Adrafinil?

Lucky for you adrafinil is actually abundantly available on the internet ecommerce scene. You can literally buy in in capsule or powder form, from many reputable sources. Retails prices will vary, but generally you can get your hands on 10g of pure powder for just under $40.


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